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Car tail qi is closely related to children’s asthma!

The incidence of children’s asthma has risen sharply since the 1950s, and has now become the most popular chronic children’s disease worldwide.

In the United States, more than 7.1 million children suffer from asthma.

In Shanghai, the prevalence of asthma in children aged 0 to 14 in 1990 was 1.75%, and in 2000 was 4.63%. In 2010, this number had increased to 7.56%, an increase of four times in 20 years.

In recent years, people have gradually understood the relationship between transportation-related environmental pollution (Traffic-Related Air Pollution (Trap) and children’s asthma.

Studies believe that TRAP causes oxidative damage in the respiratory tract, inflammation and airway reconstruction, and can induce asthma in people with genetic tendencies.

Recently, a global research published by “Liu Ye Dao Global Health” further investigated the relationship between Nitrogen dioxide (NO?) And children’s asthma incidence.

No? Pollution

NO? It is the second largest pollutant for fossil fuel burning emissions. 80%of NO? 80%in the urban environment comes from cars.

And NO? Pollution is different from PM2.5 (more discharge in low -income countries and worse pollution), NO? Pollution is less affected by regional development, and developing countries and developed countries have suffered harm. Especially in some high -income countries in North America, Western Europe, and Asia -Pacific, NO? The emissions are more prominent.

Because many countries have monitored NO? And the concentration of NO? It can well represent the emission of car exhaust and facilitate research. Therefore, related research is mostly concentrated in NO? A previous study from Canada in 2016 reported NO? Pollution and possible causal relationships between children’s new asthma.

So what did Liuye knife studied in 194 countries and found in the data of 125 major cities?

1 It is estimated that 4 million new children’s asthma can be attributed to NO? The world can be attributed to the pollution, accounting for about 13%of all new children’s asthma every year.

As a large population country, China has the largest number of newly -related asthma cases related to NO? Emissions, about 760,000.

Among them, Shanghai NO? Related children’s asthma accounted for the highest percentage of all incentives, 48%.

Although the data shows that the total number of new asthma cases related to NO? Emissions are the largest every year, the incidence of asthma in Chinese children is not the highest. According to data in 2013, the prevalence of asthma in Chinese aged 0 to 14 is 3%.

possible reason

In addition to environmental reasons, genetic susceptibility is also an important reason for children’s asthma, especially the polymorphism of 17Q21 with some genetic sites such as 17Q21, resulting in the difference in the incidence of asthma between different people in different countries.

In addition, allergies have also been confirmed to be closely related to asthma, and properly exposed to some microorganisms in the air in early stage of child development can help mature immune systems. The “over -hygienic” environment of developed countries is also related to children’s allergies.

And the researchers considering that in China, children’s asthma has not received enough attention. Many light moderate cases in clinical practice have not been diagnosed, and they may also underestimate the incidence of children in Chinese children to a certain extent.

Based on the above reasons, it explains why the incidence of asthma of Chinese children is not the highest. Nevertheless, with the environmental pollution caused by urbanization in recent years, the incidence of asthma in Chinese children should still attract our attention.

2 In different areas of the same country, the influence of NO?

64%of the newly issued 4 million new children’s asthma every year, 64%of children’s asthma occurs in the city center of various countries.

Studies have shown that the proportion of children’s asthma in the Greater City in 108 countries exceeds 50%, and this number is also consistent with the higher NO?

Among the 125 cities surveyed, Peru’s Lima is NO of every 100,000 children? The most related to asthma (690 cases per year), followed by Shanghai (650 cases), and Columbia’s capital Bobo (589 cases). Third, Beijing (569 cases) and Toronto (550 cases) in Canada followed closely.

The author’s analysis of the reasons for Beijing and Shanghai are dense population and high NO? Concentration (28 ~ 33 PPB). Children (especially children 1 to 4 years old) themselves have a high incidence of asthma, causing a large total.

3 Children’s age is also a factor that it is affected by NO? Pollution.

Because asthma has the highest incidence among children in 1 to 4 years old, children of this age are also the most caused by NO? Pollution.

The author summarizes that whether it is a developed or developing countries, especially in urban areas, the discharge of NO? Will greatly reduce the incidence of new children’s asthma. In particular, the reasons why automobile exhaust accounted for 80%of the emissions in the city. Increasing the use of new clean energy can not only improve the greenhouse effect, but also greatly improve the health of children.

references:

1.Achakulwisut P, Brauer M, Hystad P, et al. Global, national, and urban burdens of paediatric asthma incidence attributable to ambient NO2 pollution: estimates from global datasets[J]. The Lancet Planetary Health, 2019.2.Ferrante G, La Grutta s. The Burden of Pediatric Asthma. Front Pediatr.

3.zhou X, Hong J. Pediatric Asthma Management in China: Current and Future Challenges. Pediatric Drugs. 2018, 20 (2): 105-110. Doi: 10.1007/S40272-017-0276-777777

4.Xu J, Yin Y, Zhang H, et al. Paediatric asthma control under a community management model in China: a protocol for a prospective multicentre cohort study. BMJ Open. 2017;7(8):e015741. doi:10.1136/ bmjopen -2016-015741

5.chen Y Z. A National Survey in China on Prevalencence of Asthma in Urban Children. Zhonghua Er Ke ZA ZHI = CHINESE JORNAL of Pediatrics, 2003, 41 (2): 123-127.

6.The National Cooperative Group on Childhood Asthma, Institute of Environmental Health and Related Products. Third nationwide survey of childhood asthma in urban areas of China. Chin J Pediatr.2013;51:729–35.

7.Guo X, Li Z, Ling W, Et Al. Epidemiology of ChildHood Asthma in Mainland China (1988-2014): a meta -nalysis. Allergy Asthma PROC. 2018; 39 (3): 15–29. Doi: 10.250000 /Aap.2018.39.4131

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