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Cardiovasc Diabetol: It can predict the long -term mortality of patients with diabetes!

Sleep occupies about one -third of the day. As we all know, sleep is critical to a person’s health and happiness. Previous studies have shown that sleep time is related to mortality. However, the previous exploration of sleeping time can predict the subsequent long -term mortality of diabetic patients with limited research.

The purpose of this study is in patients with type 2 diabetes (T2DM), evaluating whether the metabolic status will affect the correlation between the risk of the basic sleep time and the subsequent cause/cardiovascular disease (CVD) risk.

The study was included in a total of 12526 patients with T2DM 30 years old and above, with a follow -up of more than 3 years. Investigate sleep time through computer questionnaires. Use the COX ratio risk model to evaluate the correlation between sleep time and mortality, expanded CVD, and non -enlarged CVD mortality.

The correlation between sleep time and full -cause mortality (A), expanding CVD mortality (B) and non -enlarged CVD mortality (C)

In the 10 years of follow -up, a total of 2918 deaths were recorded, including 1328 CVD deaths and 1590 non -CVD deaths. There is a “J” correlation between sleep time and full-due to mortality, expanding CVD mortality, and non-enlarged CVD mortality. The risk of death at 5-7 hours of sleep is the lowest.

Asian group analysis of sleep time and mortality correlation

The significant joint effect of the mortality rate includes ≥65 years of sleep exceeding or shorter than 7 hours (correction risk ratio [HR] 4.0), history of diabetes ≥ 5 years (1.6), diagnosis (1.69) before 45 years old, insulin using insulin (1.76), systolic blood pressure/diastolic pressure> 130/85 mmHg (1.24), glycerin trigemlene ≥150 mg/dl (1.38), HBA1C ≥ 7%(1.31), and weight index <27 kg/m2.

<!-2586: Diabetic terminal page

In short, there is a “J” association between sleep time and patients with type 2 diabetes and cardiovascular disease mortality, and the risk of death at 5-7 hours is the lowest. There is a significant synergistic role in sleep time and diabetes duration, but it has an antagonistic effect with age and obesity.

Primitive source:

Li, CI., Lin, CC., Liu, CS. et al. Sleep duration predicts subsequent long-term mortality in patients with type 2 diabetes: a large single-center cohort study. Cardiovasc Diabetol 21, 60 (2022). https : //Doi.org/10.1186/s12933-022-01500-0.

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