“Doctor, I would like to ask, do my grandson do I need to check Pymiac alpt?”
“Huh? Why check? How big is the baby?”
“3 -year -old and 2 -month -old boy. We all have it.”
“How much is the child weighing? Do you usually do not like to eat, do you feel painful?”
“Weighing 15 kg, mental appetite is good, and rarely gets sick.”
“What about people?”
“Did not bring.”
“Oh, weigh 15 kg. How much height?”
“The overall development is not bad. If this is really the case, it is not recommended to check the Pymangiopulsex.”
“No need to check?”
“No need to check.”
After getting a positive answer, grandma left briskly.
Grandma was gone, but the intern next to him whispered: “Teacher Qin, the infection rate of Helicobacter pylori is so high, do you suggest this?”
So, what is going on with Helicobacter pylori (hereinafter abbreviated as HP) infection? Why make young interns so worried? Under what circumstances do our baby must be checked and treated?
It has been confirmed that HP is a spiral microbacterium -shaped microbacterium of about 3.5 μm and a width of about 0.5 μm. It has 2-7 single poles with sheath whip hair.
At present, the gastritis caused by HP is a infectious disease, and its transmission pathway is still not completely clear, but most studies believe that most patients are transmitted through the dung and mouth -mouth transmission channels between people and people. Family aggregation. In other words, if you have a meal, if a person has HP, the chopsticks he have eaten are sandwiched in the dish, and if you go, you may be infected with HP.
In this way, it is conceivable that HP infection will be widely spread among the crowd.
According to the global infection rate of HP, the global infection rate has exceeded 50 %, and developing countries are significantly higher than that of developed countries. The higher the economy, the higher the infection rate.
my country’s infection rate is 40%to 90%(average 59%), and children are also prone to infection with Helicobacter pylori. Studies have shown that the infection rate of children under 10 years of age will reach 40% to 60%.
HP not only has a high infection rate, but also HP is very stubborn. Once an adult is infected, it will be affected for a lifetime without regular treatment, and the self -healing rate is extremely low.
In this case, isn’t it the best solution to kill HP? In other words, you can check as long as you have a willingness, and you can use the medicine directly to find out. If so, isn’t everything simple?
The fact is that many years of research have shown:
1 Most infected people have no discomfort
HP is closely related to the occurrence of chronic gastritis, digestive ulcers, gastric cancer, gastric mucosa -related lymph tissue lymphoma, so that the World Health Organization in 1994 listed it as a Class I carcinogenic factor. Nevertheless, the inflammation of the upper digestive tract caused by HP is chronic. Only 10%of which show indigestion, 15-20%manifestation as digestive ulcers, 1%to 2%of gastric cancer, less than 1%of the stomach with stomachs less than 1%. Lymph tissue lymphoma; 70 % is in a state of no obvious discomfort. In other words, although HP is calibrated as a Class I carcinogenic factor, most infected people have no discomfort.
2 Children’s infection HP has its own characteristics
The current epidemiological evidence shows that even in developed countries, most Helicobacter pylori infections occur in children. And most infections occur before 5 years old. Infected HP, people are mainly worried that it will cause children to have gastric and duodenum intestinal digestive ulcers, gastric non -cornea glandular cancer, gastric mucosa -related lymph tissue lymphoma. However, among children infected with HP, the inflammatory response or ulcer incidence of stomach and duodenal mucosa is far lower than that of adults. After a large number of studies have found that children have their own characteristics after HP infection.
(1) Children’s HP infection is very likely to have severe diseases.
Most children do not have obvious symptoms after HP infected. A small number of children can occur: abdominal discomfort, nausea, vomiting, sorb, acid reflux, black stool and other digestive tract symptoms. However, only digestive ulcers and gastric mucosa -related lymph -tissue lymphoma are referred to the HP root that are highly recommended. These two diseases mainly occur in adult infection, and the incidence of children is very low.
(2) The infection rate may be higher after children’s HP root eradication
After the adults really eradicate HP, their re -infection rate is relatively low, generally not more than 5%; children are susceptible people. Some children who are less than 10 years old are reported to be infected. Children and adults.
(3) Those with HP infection in children have a certain spontaneous clearance rate
Adult HP infection cannot be spontaneous without treatment. Once the infection is carried, it will be carried for life; in the process of their growth and development, about 10%of the spontaneous clearance rate.
(4) Drugs that can be used for children’s HP treatment are limited
Children’s HP infection treatment can be available in antibiotics and prone to adverse drug reactions. Such as levofloxacin, amurazolidone, and tetracycline should not be used for children. Due to potential neurotoxicity, the agent cannot be used for children under 6 years of age. It makes children’s HP infection treatment very difficult due to the restrictions of drug selection. (5) The compliance of children’s roots removal of HP treatment is poor
During the development of various organs systems in children, it is easy to adversely react to various drugs. In particular, it is necessary to treat HP for multiple drugs, which is more likely to cause adverse drug reactions; and children’s medication is poor. If you do not use it in accordance with regulations and courses, it is easy to cause treatment failure and secondary bacterial resistance.
3 HP may not be useless
(1) Some studies have shown that infection with HP in children may reduce the risk of children’s allergic diseases, including asthma, allergic rhinitis, allergic rash, etc.; Infection in childhood infection may inhibit the occurrence and development of diseases such as eczema, dermatitis, and other diseases. ; HP infection is also obviously negative with the risk of eczema and dust mites infection in adults.
(2) Some studies have shown that after children infected HP, the incidence of diarrhea is significantly lower than those without infected children. It is prompted that HP may be beneficial to the balance of intestinal flora. Excessive use of antibacterial drugs will increase the risk of resistance to resistance. While eliminating HP, other bacteria may also be eliminated, the balance of the flora is broken, and the potential risks are unclear.
(3) In the study of gastrointestinal diseases:
a. The incidence of obesity is significantly negatively related to the prevalence of HP infection; in developed countries, the lower the HP infection rate, the higher the obesity rate. b. Helicobacter pylori infection is negatively correlated with the occurrence of anticipant esophagitis, Barrett esophageal and esophageal adenocarcinoma, that is, it is not easy to get these diseases when there is HP infection. It can be considered that the existence of HP has a certain protective effect on patients.
(4) Research on gene sequence analysis shows that when humans moved out of Africa for the first time about 58,000 years ago, there is already a pylori infection. This reminds us that maybe HP is a human friend, and has some unclear protection effect on our body? Otherwise, it has never brought catastrophic damage to humans in such a long time.
In summary, the “Fifth National Helicobacter Pyrobiotic infection Consensus” of my country’s “Fifth National Helicobacter Cleefoxybiasis infection Consensus” is not recommended to test and treat for children under 14 years of age; ; Due to indigestion, endoscopic inspection Children’s suggestion HP detection and treatment.
What needs to be added is that the following children still need to actively test:
Chronic gastritis, gastric mucosa -related lymph tissue lymphoma, gastric cancer among first -class relatives, refractory iron deficiency anemia for unknown causes, long -term use of non -steroidal anti -inflammatory drugs (including small -dose aspirin) Chronic immune thrombocytopenia children with the cause of the cause.