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CIRCULATION: Comparison of valve degenerative heart disease in patients with type 1 diabetes and type 2 diabetes

In recent years, these diseases have made considerable progress in the pathogenesis, treatment and ending of diabetes, heart failure, and atherosclerosis. However, the role of diabetes in the occurrence and development of cardiac valve disease, especially the relationship with risk factor control.

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Recently, a research article was published on Circulation, a authoritative magazine in the cardiovascular field, and researchers were included in 71,5143 diabetes patients registered by the Swedish National Diabetes Registration Office, and compared with the 273,23333333333333333333333333333333333333333333333333333333 match comparison. The researchers analyzed the trend of incidence and COX regression, and used diabetes as a risk factor compared with the control group. Secondly, the patients with diabetes were evaluated according to the five risk factors.

The incidence of valve diseases is increasing among patients with diabetes and ordinary people. In type 2 diabetes, systolic blood pressure, weight index and renal function are related to valve lesions. Compared with the control group, almost all risk factors are risky in patients with type 2 diabetes within the target range. It is 0.64 ~ 0.70), the two -pointed stenosis is 1.95 (95%CI is 1.76 ~ 2.20), and the two -pointed return flow is 0.82 (95%CI is 0.79 ~ 0.85).

The risk ratio of patients with type 1 diabetes is: aortic stenosis is 2.01 (95%CI is 1.58 ~ 2.56), the aortic return flow is 0.63 (95%CI is 0.43 ~ 0.94), and the valve stenosis is 3.47 (95%CI CI) It is 1.37 ~ 8.84). The additional risks of type 2 diabetic patients with stenosis lesions are: aortic stenosis is 1.62 (95%CI is 1.59 ~ 1.65), and two -pointed stenosis is 2.28 (95%CI is 2.08 ~ 2.50). The ratio is 2.59 (95%CI is 2.21 ~ 3.05) and 11.43 (95%CI is 6.18 ~ 21.15). The risk of aortic valve and two -pointed valve in patients with type 2 diabetes was low, and the risk ratio was 0.81 (95%CI 0.78 ~ 0.84) and 0.95 (95%CI 0.92 ~ 0.98).

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It can be seen that the risk of stenosis disease in patients with type 1 diabetes and type 2 diabetes, while the risk of valve return flow in patients with type 2 diabetes is lower. Patients with good cardiovascular risk factors have continued to rise, and risk of valve stenosis have continued to rise, and the risks between different degrees of risk factors have no significant decrease in risks.

Primitive source:

Araz Rawshani,et al.Left-Sided Degenerative Valvular Heart Disease in Type 1 and Type 2 Diabetes.Circulation.2022.https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.058072

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