DCR: Change lifestyle can reduce the incidence of postoperative complications of patients with colorectal cancer.
Exercise has been widely proved to maintain and restore the internal stability of the level of the body, tissue, cells, and molecules to prevent or inhibit various diseases such as tumors, heart disease, hypertension, diabetes, etc. Pre -PERATIVE Exercise therapy is also reported to effectively shorten patient recovery and hospitalization time. One of the main mechanisms is that the exercise can systematically improve the patient’s cardiovascular reserves before surgery, thereby improving the overall response of the whole body response Systemic disorders tolerance. Studies have shown that there may be associated between patients’ preoperative lifestyle and postoperative complications. Therefore, this study aims to evaluate the association between the postoperative complications of patients with a pre -surgery and undergoing period of colon cancer.
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Researchers collect clinical data collection of baseline diagnosis of patients with colorectal cancer, and use questionnaires to collect data about smoking habits, drinking volume, BMI and physical activity. The occurrence of postoperative complications was collected through the case system. Multi -variable logic regression models are used to determine which preoperative lifestyle factors are related to postoperative complications.
The results of the study found that the incidence of postoperative complications of patients with colorectal cancer optional surgery was 28.5%, and the occurrence of complications would cause significant extension of hospitalization (12 days vs. 5 days, P <0.001). The risk factors related to the independent incidence of postoperative complications are ASA classification II (OR 1.46; 95% CI 1.05-2.04, P = 0.03) and III-IV (OR 3.17; 95% CI 1.96-5.12, P. <0.001), smoking status (OR 1.62; 95% CI 1.02-2.56, P = 0.04) and rectal tumors (or 1.81; 95% CI 1.28-2.55, P = 0.001). BMI, drinking and physical activity have nothing to do with postoperative complications. However, in the Asian group analysis of 200 ASA III-IV patients, high physical activity before surgery is related to less postoperative complications (OR 0.17; 95% CI 0.03-0.87, P = 0.04).
This study has confirmed changing lifestyle, such as reducing smoking and increasing physical activity, which can reduce postoperative complications of colorectal cancer surgery. In the entire research population, smoking is currently related to increased risk of postoperative complications, and high physical activity before surgery is only related to the reduction of postoperative complications in patients with ASA III-IV.
Primitive source:
Loogman， Lisanne. Et al. The Association Between Modifiable Lifestyle Factors and Postoperative Complications of Elective Surgery in Colorectal Cancer Patients. Diseases of the Colon & Rectum.2021.
