ENVIRON Res: City gray space is related to the increase in the increase in allergies of ordinary people
Air pollution can adversely affect the entire human life cycle, and it will also affect the infectious disease (that is, respiratory tract infection) and non -infectious diseases (that is, allergic diseases, chronic obstructive pulmonary disease, cardiovascular disease, lung cancer, diabetes).The degree of influence is from mild symptoms to premature death.
The building environment in urban areas may have adverse effects on children’s breathing health, while the impact on adults knows very little.
Recently, researchers from Italy published articles in “Environ Res”, who evaluated the relationship between the increase of gray space exposure and allergies in a sample of ordinary adults.
Researchers investigated the 2070 subjects (age range 15-84 years) living in PISA/Cascina, Italy, including health status and risk factors, skin spiny test (SPT), serum immunoglobulin E (IgE) and serum benzerylene glycol dilate epoxide (BPDE) -dna-DNA integrated object antibody.Through the CORINE land coverage plan (CLC 1990) in the FP7/Heals project (2013-2018), the exposure of the land coverage in the 1,000-meter buffer of each subject’s family address was evaluated.The residential address of the participants is geographically encoded and calculates the proportion of the surrounding gray space.Through the logical regression model, the potential mixed factor was adjusted, and the impact of the exposure of the gray space increased by 10%on the allergic biomarkers/conditions; it also analyzed the relationship with the positive antibody of the BPDE-DNA in the serum.Gray spaces are identified through environmental information coordination of land coverage (CLC), including multiple aspects related to urban areas, such as industrial, transportation infrastructure, and urban structural characteristics.
It was found that the gray space coverage increased by 10%and SPT positive (OR 1.07, 95%CI 1.02-1.13), seasonal SPT positive (OR 1.12, 1.05-1.19), multi-sensitivity (or 1.11, 1.04-1.19)Allergic rhinitis (or 1.04-1.17), SPT positive and asthma/allergic rhinitis (or 1.16, 1.08-1.25), asthma/allergic rhinitis (or 1.06, 1.00-1.12), there is a serum BPDE-DNA additive positive antibody (OR 1.07, 1.01-1.14).
In summary, the gray space has adverse effects on the state of allergies, and is related to the biomarkers exposed by polygon aromatic hydrocarbons in adulthood.Therefore, gray space can be used as a substitute for urban environment exposure.
<!-2377: Allergies terminal page
S Maio, S Baldacci, S Tagliaferro et al. Urban Grey Spaces are associated with increased allergy in the general population. Environment res. 2021.