Eur J Heart Fail: Higher serum selenium is related to reducing mortality and new risk of heart failure
Nutrition is a global health issue. About 800 million people in the world suffer from different forms of malnutrition. This is not limited to insufficient nutrition, but also includes specific trace nutrient deficiency caused by developing countries and developed countries due to imbalance. Eating habits may play an important role in the occurrence and prevention of chronic non -infectious diseases related to nutrition.
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Recently, a research article published a research article on EUROPEAN JOURNAL of Heart Failure in the cardiovascular field. Researchers aims to clarify the relationship between serum selenium level and death and new heart failure in general adults.
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In the Dutch queue, the researchers measured the serum selenium level and conducted a retrospective analysis of the forward -looking evaluation data. The main ending indicators of the study are the incidence of mortality and new heart failure (HF), and it is combined with it as the complex end.
The serum selenium level was measured among 5973 subjects, and the average serum selenium concentration was 84.6 (± 19.5) μg/L. The average age is 53.6 (± 12.1), and 3103 subjects (52%) are women. The median follow -up time is 8.4 years. The level of serum selenium is positively correlated with the high total cholesterol and blood glucose concentration, which is negatively related to anemia, iron deficiency, current smoking, C -reactive protein levels and higher weight indexes. Analysis of single variable variables of all subjects shows that there is no association between 10 μg/L and complex endpoints for each increase (risk ratio [HR] = 0.96, 95%confident interval [CI] to 0.87-1.06, P = 0.407)))) Essence However, researchers have observed significant interactions between serum selenium and smoking state. In non-smoke-absorbing subjects (n = 4288), the decreased serum selenium concentration and mortality rate (HR = 0.87, 95%CI is 0.79-0.96, P = 0.005), new HF risk decrease (HR = 0.82, 95% The CI is 0.69-0.96, P = 0.017), and the risk of composite end point (HR = 0.86, 95%CI is 0.79-0.94, P = 0.001). The researchers did not observe the association among smoking subjects.
It can be seen that serum selenium concentration is independent of multiple indicators of metabolic syndrome. In addition, the high level of serum selenium is related to the mortality rate of non -smokers and new heart failure. Study research is required to evaluate the potential benefits of selenium supplementation, especially for people who do not smoke.
