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Houttuynia cordata contains “aristolochic acid”, which has renal poison and is carcinogenic?Can the Houttuynia cordata else eat it?

“I can’t eat folding roots in the future! It will get liver cancer!” Aunt Su’s words made all relatives of the family boiling.



Dasao: Don’t talk about this, Sichuan people, who does not eat Houttuynia?

Auntie: What is going on, and why does it have a relationship with liver cancer?

Uncle: Houttuynia cordata is all treasures, don’t listen to rumors.

Aunt: In case it is true, then it is incredible. Can this Houttuynia cordata eat it?

When Aunt Su saw the big guy arguing endlessly, she quickly saw the article he saw “Don’t eat Houttuynia cordata again, with renal toxicity and carcinogenic!” “The article was forwarded to the group, and explained that some studies have found that aristolochic acid has strong renal toxicity and carcinogenic, and Houttuynia corday contains a lot of aristoline!

There are articles and research, which seems to be the same as that of “stone hammer” Houttuynia cumata. Now that relatives have messped up and began to worry about whether they would really suffer from liver cancer.

So, what is the truth, what is going on? Is Houttuynia a “poison”?


1. What is the relationship between aristolochic acid and cancer?

The relationship between the aristolochic acid and cancer has a lot of arguments many years ago, followed by Xiao Miao.

In 2001, the US Drug Administration warned to remind consumers not to consume plant -based products containing aristolochic acid.

In 2008, aristolochic acid was listed as a type of carcinogen by WHO, that is, substances that have a clear carcinogenic effect on humans.

In 2013, two articles were published in “Science · Transformation Medicine”, which pointed out that aristolochic acid was related to a specific gene mutation in cancer cells. In other words, aristoline may lead to mutation of genes in the patient’s body and eventually induced cancer.

In 2017, a study was published again in “Science · Transformation Medicine”. The researchers selected 1,400 patients with liver cancer for investigation to count the proportion of genetic mutations related to aristolochic acid related genes in the subject. It was found that the relevant proportion of mainland China reached 47%, and the Taiwan region reached 78%!

However, these studies only indicate the correlation between the aristolochic acid and cancer, and there is no relationship between the “real hammer”.

Until 2019, researchers at Shanghai Jiaotong University found in mice experiments that shooting mice for mice will cause mice to suffer liver cancer, and the larger the amount of injection The higher the degree of malignant.

For the first time, the study confirmed the connection between aristolochic acid and cancer, and once again, the aristoline was pushed to the cusp.


Second, do Houttuynia cordata really contain aristolochic acid? Can you still eat it?

It is rumored that Houttuynia cordata contains aristolochic acid. Long -term consumption not only hurts the kidneys, but also causes cancer. Is this true?

In fact, this statement has long been denied by the Food and Drug Administration.

First of all, Houttuynia cordata is a three -white grass plant, not a macular plant, but a three -white grass plant.

Secondly, the aristolin (BII, ALL, FII) contained in Houttuynia cordata (BII, ALL, and FII) is completely different from the carcinogenic aristolochic acid metabolic ⅰ ⅰ. The name is similar, and the nature is not the nature. Similarly, the two should not be equivalent, do not confuse.

Coupled with the low content of the macular basin in Houttuynia cordata. Li Yun, the Risk Monitoring and Evaluation Research Office of the Agricultural Product Quality Standards Research Center of the Ministry of Agriculture, also pointed out that there is no evidence at this stage indicating that Houtturaching is carcinogenic.

At present, the “Product Catalog of the Implementation of Pinnic Agricultural Product Certification” and “Chinese Pharmacopoeia” have attributed Houttuynia cordata to the list of medicines and foods. Therefore, there is no correlation between eating Houttuynia cordata and kidney damage and cancer, and there is no need to panic.


Third, those who really contain aristolochic acid are these Chinese medicines

For those who love to eat Houttuynia cordata, you can rest assured that you don’t have to worry about eating. What really needs to be vigilant should be these Chinese medicines containing aristolochic acid. You must avoid daily.

Guan Mutong, Guangfang Ji, Aoki, Tianxian Teng, Matspen, Asarum, cinnabar lotus, Tengxiang and other Chinese medicines all contain aristolochic acid.

Around 2002, many countries and regions issued the use of the use of Chinese herbal medicines for aristolochia.

The my country Pharmaceutical Bureau has also canceled the medicinal materials standards of Guan Mutong, Guangfang Ji, and Aoki in 2003, and removed these three Chinese medicines out of the “Chinese Pharmacopoeia” to prohibit sales and use.

For other Chinese medicines containing aristolochic acid, it also clearly stipulates that it is necessary to manage according to the standard of prescription drugs, and must not be abused.

Zhang Ning, Wangjing Hospital of the Chinese Academy of Traditional Chinese Medicine, reminded: There are three clinical manifestations of kidney injury of Chinese herbal medicine, and people who take Chinese medicine should be vigilant.

1. Acute renal failure: Patients can take a large amount of medication in a short period of time or within a week.

With the development of practice, the symptoms of acute renal failure such as low urine and urine -free. Medical examinations will find that patients have acute renal tube necrosis. The prognosis of this type of failure is generally better, and renal function can be restored by treatment. 2. Chronic renal failure: Long -term continuous and intermittently taking drugs with renal toxicity can induce chronic renal failure. In the early days, the function of renal tubular function was performed, but the level of serum creatinine and urea nitrogen was normal.

Over time, patients will have abnormal renal function, and different patients will have different diseases, and they will be more than half a year. The prognosis of this type of disease is poor, and it is difficult to restore patients by treatment by treatment.

3. Rena dysfunction: The patient’s condition is mild, manifested as renal tube concentration, damage to the function, etc., but the renal function is basically normal. Mostly manifestations are increasing luminuria, proteinuria, and under -mirror hematuria, etc., which can return to normal by treatment.

In the end, Xiao Miao made a summary for everyone that Houttuynia cordata will not hurt the kidneys and do not cause cancer. What really needs to be vigilant is those traditional Chinese medicines containing aristolochic acid. Chinese medicine needs to be directed by professional doctors to avoid unnecessary threats to their health.

Reference materials:

[1] “Overview of Chinese Herbal Medicine Kidney Damage”.

[2] “Chinese Medicine Say | Rasal Bell acid is carcinogenic, can Houttuynia cordata else eat it? “.

[3] “It is confirmed that the aristoline” can directly lead to liver cancer! ” Pay attention to these traditional Chinese medicines … “. Medical community. 2019-08-01

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