Editor choice

How much do you know how to make women embarrassed?

The high incidence of polymorphosis in children of childbearing age is an endocrine disease that cannot be underestimated on women’s psychological impacts and requires positive treatment. This article reviews this disease.

Female hair is a common clinical phenomenon in women, and the incidence of childcare women is about 10%. Generally, the increase in the hair of therogen -dependent parts, and the expression parts include the upper lip, chin, ears, cheeks, lower abdomen, back, chest, chest, and limbs too much hair.

The cause of polymorphosis

1. Mao hair caused by ovarian diseases: The most common in polycystic ovarian syndrome, accounting for about 90%of polymeris. Its typical clinical manifestations are irregular menstruation, infertility, obesity and hair.

2. Mao hair caused by adrenal diseases: (1) Congenital adrenal cortex hyperplasia is the hidden inheritance of ingredients, and the lack of 21-hydroxylase is the most common. Due to this lack of this enzyme, the synthesis of cortisol is reduced, and the feedback promotes the secretion of adrenal corticosteroid ACTH to compensate the insufficient synthesis of cortisol, which then leads to a large number of and secretion ofrogen in the middle product. (2) adrenal tumors: adrenal adrenal tumors that are simply secreted byrogens are rare, and they are mostly accompanied by masculine manifestations. (3) Ku Xin syndrome: Whether it is the adrenal cortex tumor, heteroidal endocrine tumor or pituitary secretion of Ku Xin disease, it can promote excessive secretion of cortisol and interstitial androgens, inducing polymorphism.

3. Medica Mao Mao: Exogenous androgen can cause hair. Methyl testosterone, danzole, and other synthetic steroids can cause excessive growth and acne.

4. Mao hairpinis: polymorphism that cannot be determined. Patients with 5%to 6%of hair disease are such categories. The cause may be related to the sensitivity of the cell receptor of the outer hair follicle sebaceous glands in the peripheral hair follicles, and the increase of 5α-reducing enzyme activity enhancement.

Diagnosis of Mao

First of all, the patient should be carefully asked about the speed of the disease and the progress of the disease. The menstrual cycle and the history of medication are different. Due to the different causes and treatment of polymorphosis and masculine and hair. Mao and masculine age and progress of progress can provide valuable identification basis. For example, adrenal androgen secretion tumors and follicular membrane cell proliferation are moving rapidly, and the masculinity is obvious; and general cubic syndrome and polycystic ovarian syndrome are progressing slowly.

The total amount of blood testosterone should be measured in laboratory examination, such as the total amount of blood testosterone <0.6ng/ml and the menstruation is normal, and there is no need to do further examination. If the total amount of blood testosterone is ≥0.6ng/ml, the accompaniment or scarce menstruation should be determined first to eliminate high PRL blood disease, and use B -ultrasound to further eliminate the polycystic ovary syndrome.

When highly suspected of congenital adrenal cortex hyperplasia, blood measurement should be added to 17-OHP or further adrenal image examination. Except for the slight increase in blood testosterone and other examinations, the diagnosis of the polycystic ovary syndrome is basically established.

Treatment of Mao

Cause treatment is the basic principle of hairy disease (such as the treatment of adrenal or ovarian tumors). The treatment of polymorphism includes non -drug treatment and drug treatment. The former includes shaving and hair removal, electrolyte removal and laser hair removal. Because most patients have high androgens, non -drug treatment cannot prevent the regeneration of hair and need to be treated with drugs.

There are many drugs currently used to treat women with hair. The common choices are as follows:

Oral contraceptives: In 2008, the clinical practice guidelines of the Inpirin Society recommended oral contraceptives as the preferred plan for hairpinomy. Oral contraceptives can inhibit the secretion of luteal gogen (LH) and reduce LH -dependent ovarian androgen synthesis. Generally, it contains 30 ~ 35 μg of diaryol to achieve an effective inhibitory of LH.

Screw is similar to progesterone, which can inhibit the synthesis of steroid hormones, antagonize the role ofrogens, and inhibit the 5α-reducing enzymes particularly obvious. The use of snails starts 2 times a day from 50mg, and gradually increases to 100mg 2 times a day. Overall tolerance is good, adverse reactions include hypertrophy, gastrointestinal discomfort, breast pain, and irregular menstrual bleeding. The mechanism of scrok is different from oral contraceptives. For example, the combination of two drugs has a good effect on the polycystic ovary syndrome and unique hair.

Nonichamine: non-Naruramine inhibits type 2 5α-reducing enzyme activity, but it has no effect on type 1 5α-reducing enzymes. It is mainly used to treat prostate hyperplasia and can also be used for hairy disease. The general dose is 5mg/d, which can be visible after 6 months of treatment.

Flobatamine: Anti -anticukerogenia is strong, mainly used to treat prostate cancer. It may have a considerable effect when treating hairpinis, but it may induce liver injury. It is not recommended to be a regular medication for hair.


All these drugs are inhibitory. Discontinuation will cause symptoms to recur, so women of childbearing age should be continuously used. During pregnancy, all drugs, especially anti -androgen drugs. It takes a certain time (at least 6 months) to show the effectiveness of the effect, and then you can consider whether to change the dose, change or add medicine.

1 Comment
  1. Way cooⅼ! Some very valіd points! I appreciate you writing this
    wrіte-up and also the rest of the site is extremely goоd.

    Leave a reply

    Health Of Eden
    Enable registration in settings - general
    Shopping cart