Alzheimer’s physical and mental health is harmful to the elderly. The elderly are mainly divided into three types. The most common is Alzheimer’s disease, followed by cerebrovascular dementia. The third is caused by infection, tumor, trauma, etc. Very few. The cognitive ability and memory function of Alzheimer’s patients will continue to deteriorate, gradually daily life ability cannot take care of themselves, and various nerve and mental symptoms and behavioral disorders will occur. The elderly who have dementia need to be treated for a long time. What are the commonly used drugs?
There are mainly the following common drugs for treating Alzheimer’s:
1. Improve the choline neurotransmitters:
One of the main reasons for Alzheimer’s dementia is insufficient choline, which leads to loss of memory, loss of orientation, behavior and personality changes. Therefore, drugs with the effect of enhancing choline play an important role in the treatment of dementia. The current 4 commonly used are acetylcholine enzymes (ACHE) inhibitors, including other Klin, Andershen, Aceneng, Galana (the other is N-methyl-D-天 目前 目前 (NMDA) Receptor antagonist, U.S. Vajra hydrochloric acid).
2. Drugs to improve cerebral blood circulation and brain cell metabolism:
Alzheimer’s patients with metabolic disorders such as sugar, protein, nucleic acid, lipids, etc. At the same time, their cerebral blood flow and oxygen consumption are significantly lower than normal people of the same age. Therefore, brain metabolic excitement and brain circulation improvement agent, especially the brain metabolic excitement with the function of cerebral vascular dilatation, has become a major category of dementia for choice. Such drugs such as brain recovery, all cocoa, happy town, heyone cocoa alkali, brain through the brain.
3. Calcium antagonist:
Such drugs are easy to selectively expand cerebral blood vessels through blood -brain barriers, reducing nerve cell damage or death caused by calcium ions, thereby improving memory and cognitive functions.
4. Hormone drugs:
The use of estrogen to treat Alzheimer’s disease can relieve the symptoms of female patients and delay or prevent the development of patients. Studies believe that the role of estrogen is related to its antioxidant, reducing the damage to cells in the sedimentation of amyloid -like protein, promoting the repair of neurons, and preventing nerve cell death.
5. Non -steroidal anti -inflammatory drugs:
The risk of elderly people who often take aspirin or anti -inflammatory and analgesic drugs have significantly reduced the danger of dementia and cognitive obstacles. Small doses of aspirin can reduce dementia. This is because aspirin has the effect of enhancing cerebral blood flow and preventing blood coagulation. In addition, non -steroidal anti -inflammatory drug ibuprofen, bislofen acid, Nisson, etc. may all become effective drugs for treating Alzheimer’s disease.
6. Free radical clears and antioxidants:
Vitamin E is an important antioxidant. It has the function of free-radical metabolism. It may also produce the β-starch-like protein deposition in the brain to delay aging. Other free radical cleansing agents include melanin, curculinin, deoxintelin, molar pyrodine, and molar sulfonic acid. Vitamin C has the effect of clearing free radicals and antioxidant, which can stabilize the cell membrane.
7. Venom alkali receptor agonist:
High doses of toxicine -alkali M1 receptor agonist accounted for Nonomelin, which can significantly improve the cognitive function and action behavior of elderly dementia patients. However, due to the severe side effects of the gastrointestinal and cardiovascular, many patients cannot continue treatment.