Infertility is usually defined as descendants of humans, animals or plants through sexual reproduction. Previous reports showed that in high -income countries, the prevalence rate of male infertility within 12 months was 3.5 % to 16.7 %, and low -income countries were 6.9 % to 9.3 %, and the overall median prevalence was about 9 %. According to the National Health Insurance Research Database (NHIRD), the quality of male sperm in the world has declined in the past few decades, among which male factor accounts for about half.
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For men, infertility is caused by congenital and acquired factors, and obesity and metabolic syndrome have been considered an important factor in male infertility. Among the people of obesity and metabolic syndrome, it is often accompanied by obstructive sleep respiratory, while research shows that the severity of obstructive sleep apnea is related to male infertility, but the results of the research are not consistent. Recently, a study published in Jama Oncology showed that the relationship between obstructive sleep apnea and male infertility.
In this study, the researchers stated the 4607 male patients diagnosed from Taiwan from January 1, 2000 to December 31, 2013 from the Taiwan Health Insurance Database (NHIRD). Sperm -free, erectile dysfunction, early ejaculation and infertility caused by testicular causes. After passing the multiple guidance of sleep diagram, patients with obstructive sleep respiratory suspension patients were diagnosed and patients were performed at least 3 outpatient clinics or 1 case of hospitalization.
The results of the study show that the risk of infertility of patients with complications has increased significantly, including hypertension, diabetes, hyperlipidemia, chronic obstructive pulmonary disease, chronic kidney disease, coronary heart disease, liver cirrhosis, obesity, anxiety and depression disorders Wait. Compared with the control group, the risk of infertility of patients with obstructive sleep apnea is 1.24 times higher. At the same time, patients less than 40 years old have high infertility risk, and obstructive sleep respiratory suspension seems to be an independent risk factors for infertility.
Specifically, in all ages, the suspension of obstructive sleep and respiratory risk is related to the increase in infertility, except for people 40 or 40 years old. The infertility risk of men with obstructive sleep apnea and complications increases significantly, and hypertension is a significant risk factor. In addition, as the interval between obstructive sleep breathing exposure time increases, the risk of infertility has increased significantly. In the interval between more than 5 years of exposure, the infertility risk of patients with obstructive sleep and respiratory suspension is higher than those who have not affordable sleep. In addition, patients who have not accepted obstructive sleep apnea are higher risk of infertility.
In summary, obstructive sleep respiratory suspension is a common sleep disorder, which stops intermittent respiration caused by repeated collapse of the pharynx during sleep. Obstructive respiratory suspension is still related to male infertility, and it is related to the time of the risk exposure. Therefore, obstructive sleep apnea intervention measures and early identification can reduce the risk of subsequent complications including infertility.
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Yi-Han Jush, Association of ObStructive Sleep apnea with the risk of male information in Taiwan.jama network. 2021; 4 (1): e2031846.