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New gameplay: “Eating shit” to treat fatty liver?

“The circle of friends went to the hospital to donate 200 yuan to the hospital, it turned out to be true.”

In recent years, many hospitals at home and abroad have issued a call for “donation of feces”. Volunteers donated can usually receive free medical examinations and receive subsidies ranging from 200-500 yuan, which has attracted widespread attention and heated discussion.

Yes, you read it right, it is “donating shit”! Although the feces sound indecent, they can play a huge role in a doctor. All of them benefit from a new technology -FECAL Microbiota Transplantation (FMT), let’s take a look ~

What is feces transplantation?

The intestinal tract of the human body is set to a huge bacteria with a large number of types and quantities. It is closely related to human health. When the type or number of intestinal flora changes, it may cause the occurrence and development of certain diseases, such as pseudo -membrane enteritis, inflammatory bowel disease, intestinal exciting syndrome, non -alcoholic fatty liver, etc.

FMT is a technology based on the intestinal flora. It means that after a series of separation and purification of functional flora in healthy human feces, transplants into the patient gastrointestinal tract through endoscopy or drainage tube, rebuild new intestinal bacteria Groups, thereby treating intestinal and extra -intestinal diseases. Separation and purified bacteria from feces are complicated, containing a large amount of probiotics and symbiotic bacteria, which are very close to the physiological situation of the human body. It has good therapeutic effects on some diseases caused by intestinal flora disorders.

What diseases can FMT treat? What is the effect? At the Academic Annual Conference of the Chinese Medical Association Liver Disease Branch on September 13, 2020, Professor Zhou Yongjian, the Department of Gastroenterology, the First People’s Hospital of Guangzhou, introduced the clinical application of FMT technology in the clinical application of the digestive liver disease.

Studies have confirmed that feces transplantation can treat intestinal diseases

Professor Zhou Yongjian introduced that the earliest FMT technology was used to treat ulcerative colitis and shared a case.

Patient 40 years old, female, diagnosed with chronic recurrent ulcerative colitis, left half colon type, moderate activity, and seeking medical treatment. Creative ulcerative colitis. When Professor Zhou Yongjian was visited, the colonoscopy was very serious. After 3 months of treatment of FMT, the symptoms of mucosal healing were basically improved. Symptoms such as mucosal healing and mucus and blood stools were significantly relieved, and the curative effect was very ideal.

Professor Zhou Yongjian and his research team have confirmed that FMT has a good effect on the treatment of ulcerative colitis and intestinal syndrome for FMT. Studies have shown that FMT can significantly reduce the Mayo score of patients with ulcerative colitis and improve the intestinal flora; it can significantly improve the quality of life of patients with intestinal syndrome.

The latest research found that fecal bacteria transplantation may treat fatty liver

Nonalcoholic Fatty Liver Disease (Nafld) is a metabolic stress liver injury related to various factors such as insulin resistance, genetic, and environmental factors, and is also considered a manifestation of metabolic syndrome in the liver. In recent years, more and more studies have shown that the intestinal flora has also played an important role in the occurrence and development of NAFLD.

Under normal circumstances, only a small amount of bacteria in the intestine enters the liver through the vein of the door, and can be swallowed by the macrophages in the liver. When some pathological conditions occur, such as damage to the intestinal mucosal barrier function, the bacterial and bacterial products that enter the liver increased, the immune balance is broken, the bacteria and its products cannot be effectively cleared. Extract inflammation.

Professor Zhou Yongjian and his research team confirmed through experimental studies that intestinal flora disorders can cause and aggravate liver inflammation and fibrosis. In the animal model, whether it is a low -fat diet or a high -fat diet, the disorders of the intestinal flora can induce liver fat changes. After correcting the flora disorders, the inflammation and fibrosis of the liver have improved significantly.

Professor Zhou Yongjian introduced that the clinical application of FMT treatment Nafld has achieved good results and is currently carrying out related clinical trials of FMT treatment NAFLD.

As a new technology, the security of FMT is also an important issue. Professor Zhou Yongjian summarizes FMT’s adverse events based on more than 1,000 FMT data that has been completed. 15%of the people have an excessive fever, and 70%of the anal exhaust increased in 1-2 days after the art of human surgery, an excessive abdominal pain, etc. No serious adverse reactions were seen.

Professor Zhou Yongjian analyzed that the serious adverse incidents reported by some literature may be related to the loopholes or improper operation of donating feces. Therefore, the clinical application of FMT needs to strictly control the interruption of supply screening and fecal bacteria (“donating shit” also has a threshold, and your stool must be “healthy and good” by thousands of miles).


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