Under normal circumstances, there is a protective layer between testicular tissue and blood that supplies testicular nutrients. Medically, it is called a blood test barrier. This barrier can prevent certain substances in the blood from entering the testicles. However, many drugs can pass the blood test barrier, which affects the function of the testicular, interfere with the formation of sperm, and affect the health of sperm eggs in two methods.
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The first is to interfere with the formation of sperm. For example, some common immunomason, such as cyclopensions, nitrogen mustard, long -chunnex, cisplatin and other drugs, have a strong toxic effect and can directly disturb the synthesis of sperm DNA, including changes in genetic material components, chromosomal abnormalities and sperm malformations. Essence There are also morphine, chlorobylzine, erythromycin, Lifuping, heat -relieving painkillers, ciprobine (artificial antibiotics), ketoconazole (antimybal medicine), etc. These drugs affect sperm fertilization by interfere with the synthesis of androgen, such as male infertility and women’s habitual abortion (early embryo loss). Some of them are the result of the damage to male sperm.
The second is that these drugs enter the testicles through the blood test barrier. They can be discharged into the vagina with the semen produced by the testicles, and after the vaginal mucosa is absorbed, the blood circulation is entered, which increases the incidence of low -weight and deformity tires, and also increases the mortality of the fetal fetus.
In addition, there are some drugs that can also enter semen, such as extinguishing dripping, aminoin, phenibyline, and diezyinhein, but the current research is not very clear about how they affect sperm, fertilized eggs and fetuses.
In addition, drugs that affect men’s sexual life will also indirectly affect eugenics and educated education. The following drugs are not available at random.
Various sex hormone drugs: such asrogen and Krumin, which can affect the endocrine function of the human body. Doctors are often used to treat endocrine diseases. However, these drugs are double -edged swords, which are properly used to help fertility; improper use to inhibit sperm development. When the prospective father uses estrogen and progesterone drugs, it may also cause sexual pleasure to reduce sexual pleasure, rapid decrease in sexual desire, or even disappear, which affects ejaculation function.
In addition, glucocorticoids such as strong pine, dexamethasone, etc. If you apply it in large quantities for a long time, it will also reduce the sexual function of the prospective father and harm the health of the sperm.
Diuretic drugs, such as the body of the body, have anti -male hormones. If they are used for a long time, they will reduce sexual function and harm sperm. In addition, dual -hydrogen hydrogen urine plugs can also reduce sexual function; rapid urine (sarci, furaine) and uric acid (butadyxoxic acid, bundlebini) can induce hybrids, and sometimes erectile dysfunction occurs. However, the situation can be changed after adding potassium salt.
For example, the blood pressure of hypertension, even if the dose is small, will affect the sexual function of most male patients, and even cause cannot ejaculate. Some can induce depression, so that the original sexual dysfunction and Low sexual desire is even more serious. Therefore, the prospective father should not choose the blood level. Pyrine also easily causes the penis to be erected, ejaculated, or even ejaculation.
Cardiovascular drugs, such as common metamopapopa, pyrazine (thozide), megamin, oligazine, and colas that treat glaucoma and hypertension, the ocean, ground high, and high scholarship of coronary heart disease, Gaoxin, high ground, high ground, high ground, high ground, and high ground, high ground, high ground, high ground, and high ground, and high ground, high ground, high ground, and high ground, and high ground, and high ground, and high ground, and high ground, and high ground, high ground, high ground, and high ground. Strong soul can lead to decline in male sexual function. The experience of treating arrhythmias (Pukolol, Heart Annan), and the dose is slightly increased, it is easy to have side effects such as weakening sexual desire and penile erection.
Chinese herbal medicine: Most Chinese herbal medicines are natural plants, with little side effects. However, for dads, Chinese herbal medicine is not absolute insurance. For example, Legongjo has not light lethality for sperm. In addition, the prospective dad in cotton -producing areas should pay special attention to do not eat cottonseed oil, otherwise it will also misunderstand the fertility plan.
Immunomantic regulators such as cyclumamide, nitrogen mustard, cisplane and other drugs. It has a strong toxic effect and can directly disturb the synthesis of sperm DNA, including changes in genetic material components, chromosomal abnormalities and sperm malformations. Like male infertility, women’s habitual abortion (early embryo is lost), some of which are the result of the damage to male sperm.
These drugs can also be discharged into the vagina with the semen produced by the testicles. After being absorbed by the vaginal mucosa, the blood circulation is entered, which increases the incidence of low -weight children and deformities, and increases the mortality of the fetus during the perinatal.
Among the more commonly used drugs, anesthesia and immunomaggtic regulators can be used to increase the incidence of low weight and deformity tires through the above channels, and it will increase the opportunity of the death of newborn in the perinatal period. In addition, there are extinguishing glory, erythromycin, amino cyanomycin, pentamoxylxylthyl, metharomycin, phenibinhamine, and diezylinin, which can enter semen and affect fetal development.
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There are also some drugs to reduce the quality of sperm, including changes in genetic material components, abnormal chromosomes, and sperm malformations, which may lead to decline in the quality of conception and affect the development of future generations. Such as hydrochloride, flimromycin, and tiomalzide and other drugs have this role.
Therefore, in the 2-3 months and pregnancy period before pregnancy, the husband must be careful with medicine. If possible, it is best to stop all drugs.
(Editor in charge: Zhang Can City)