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What is the correlation of the risk of type 2 diabetes from childhood to early adults?

At present, the lifestyle intervention that is designed to reduce the weight of adults can delay the onset of type 2 diabetes of type 2 diabetes in type 2 diabetes. Among children, it is now determined that even at the level that is far lower than the current overweight classification, the higher physical index (BMI) value is also related to the increase in risk of type 2 diabetes. So, can ultra -weight or obese children lower the risk of adult diabetes in adulthood? In this context, Danish researchers have studied whether to reduce this risk before an adult. Study published in Nejm magazine.

Researchers were included in the 62565 -year -old, 13 -year -old and early adults (17 ~ 26 years old) Denmark men, and measured their weight and height. Definition of overweight according to the standards of the US Disease Prevention and Control Center. Data from a national hygiene registration system obtained data about type 2 diabetes (at the age of 30, 6710 people).

Main result

At the age of 7 (3373 of the 62565 people; 5.4%), 13 years (3,418 of 62,565; 5.5%) or early adults (5,108 of 62,565; 8.2%), the risk of overweight and type 2 diabetes was positive at the time. Related; when the overweight age, the age of the diagnosis of type 2 diabetes, the correlation is stronger. Among men who eliminate overweight before the age of 13, the risk diagnosed as type 2 diabetes at the age of 30 to 60 is similar to that of men who have never overweight (risk ratio, 0.96; 95% CI, 0.75 ~ 1.21). Compared with men who have never overweight, men who are overweight at the age of 7 and 13 but not overweight in the early adults are more risk for type 2 diabetes (risk ratio, 1.47; 95% CI, 1.10 ~ 1.98), but they The risk is lower than the continuous overweight (risk ratio, 4.14; 95% CI, 3.57 ~ 4.79). The increase in physical indexes from the age of 7 to an early adult is related to the increase in risk of type 2 diabetes, even if the men who have a normal weight at the age of 7.

discuss

This large -scale vertical study shows that men who are overweight at the age of 7 to 13 and then maintain normal weight in early adults. Type 2 diabetes risk is similar to men with normal age and weight. Men who are eliminated in the early age of 13 to early adults have a risk of type 2 diabetes than men who have never overweight, but lower than men who are overweight in all inspections.

Therefore, the data shows that in this research crowd, if men who have overweight children eliminate overweight before adolescence (that is, before the age of 13), the risk of type 2 diabetes is low. After the age of 13, men who eliminate overweight before adulthood, the risk of type 2 diabetes was significantly lower than that of men at all ages. Compared with overweight in early adults, the risk of type 2 diabetes that are overweight in adolescence and early adults. Because adolescence overweight seems to be a particularly important factor in the increase in risk of type 2 diabetes in the middle and later periods, it may be possible to reduce the risk of BMI before these age.

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