In recent decades, with the rapid development of socio -economic and changing lifestyle, the prevalence of non -alcoholic fatty liver disease (Nafld) has risen sharply globally. It is estimated that more than 1/4 individuals around the world have Nafld, which has become one of the most common chronic diseases. However, because the damage of Nafld is usually chronic and asymptomatic, the actual prevalence may be underestimated. Therefore, the important risk factors of NAFLD as soon as possible are the clinical needs that need to be solved urgently. Limble (WC) and Body Quality Index (BMI) are the most widely used indicators for evaluating obesity and Nafld. In recent years, in -depth research has found that the height ratio of the waist circumference (WHTR) can better evaluate the central obesity, diabetes, diabetes , Hypertension and other metabolic diseases. Therefore, this study aims to explore the connection between WHTR and NAFLD.
In this study, a total of 1,4125 participants were included in. In order to better understand the connection between WHTR and Nafld, the researchers made the WHTR value group into a five -point number and used the multi -variable logistic regression model to evaluate the Whtr and its five -point points. Bit and NAFLD risk. In addition, using a broad -featured model to model the association between WHTR and NAFLD to explore the non -linear relationship between them.
The prevalence of NAFLD among participants in this research is 17.59 %, with an average age of 43.53 ± 8.89 years. Researchers found that every unit increased by WHTR, Nafld risks increased by 66 %. In addition, in the five -point array of WHTR, the participants with the first bit and five points, the 2nd five points, the 3rd five -point digits, the 4th five -point, and the 5th five -point digits Nafld risks increased by 3.62 times, 5.98 times, 9.55 times and 11.08 times, respectively. Non -linear relationship analysis reveals the threshold and saturation effect between WHTR and NAFLD. Among them, about 0.4 is the threshold effect of NAFLD risk, and 0.6 may be the saturation effect of NAFLD risk. In addition, the Asian group analysis shows that the interaction between WHTR and BMI is significant.
The results of this study show that among adults, WHTR is related to the increase in incidence of Nafld, and the association is not pure linear but non -linear, with significant thresholds and saturation effects.
Guotai sheng. Et al. WAIST-to-Height Ratio and Non-Alcoholic Fatty Liver Disease in Adults.